This lecture revisits Manus x Machina, the popular 2016 summer Costume Exhibition which featured more than 170 examples of haute couture and avant-garde ready-to-wear, dating from the early 1900s to the present. The exhibition addressed the founding of the haute couture in the 19th century, when the sewing machine was invented, and the emergence of a distinction between the hand (manus) and the machine (machina) at the onset of industrialization and mass production. The lecture explores this ongoing dichotomy, in which hand and machine are presented as discordant tools in the creative process, and questions this relationship and the significance of the long-held distinction between haute couture and ready-to-wear. Structured around the traditional métiers of the haute couture, the lecture will virtually tour the show’s demonstration of the petites mains workshops of embroidery, featherwork, and artificial flowers, as well as pleating, lacework, and leatherwork through exquisite works of fashion. Traditional hand techniques are discussed alongside innovative technologies such as 3-D printing, computer modeling, bonding and laminating, laser cutting, and ultrasonic welding.